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In the acute phase, venous thrombosis of the extremity can be associated with significant swelling, pain and pulmonary embolus associated with respiratory and even life threatening deoxygenation. Chronically it can lead to delayed swelling and pain - especially with limb dependency or exercise). In fact, venous thromboembolism (VTE) in children is associated with significant short- and long term morbidity and mortality when compared to the general population .
While the etiology is multifactorial, VTE events correlate to an imbalance of the intrinsic coagulation balance as described by Virchow over a century ago . In the pediatric population, VTE events generally coincide with immobility, recent surgery, inflammation, and/or ongoing critical illness - factors often observed in the inpatient setting .
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Last updated: May 13, 2019
Drucker, Natalie A, et al. "Venous Thromboembolism." Pediatric Surgery NaT, American Pediatric Surgical Association, 2019. APSA Webapp, www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829820/all/Venous_Thromboembolism.
Drucker NA, Dalsing M, Wang S. Venous Thromboembolism. In: Waldhausen J, Powell D, Hirschl R, eds. Pediatric Surgery NaT. American Pediatric Surgical Association; 2019. https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829820/all/Venous_Thromboembolism. Accessed October 18, 2019.
Drucker, N. A., Dalsing, M., & Wang, S. (2019). Venous Thromboembolism. In Waldhausen, J., Powell, D., & Hirschl, R. (Eds.), Pediatric Surgery NaT. Available from https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829820/all/Venous_Thromboembolism
Drucker NA, Dalsing M, Wang S. Venous Thromboembolism [Internet]. In: Waldhausen J, Powell D, Hirschl R, editors. Pediatric Surgery NaT. American Pediatric Surgical Association; 2019. [cited 2019 October 18]. Available from: https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829820/all/Venous_Thromboembolism.
TY - ELEC
T1 - Venous Thromboembolism
ID - 829820
A1 - Drucker,Natalie,MD
AU - Dalsing,Michael,
AU - Wang,S. Keisin,MD
ED - Waldhausen,John,
ED - Powell,David,
ED - Hirschl,Ron,
Y1 - 2019/05/13/
BT - Pediatric Surgery NaT
UR - https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829820/all/Venous_Thromboembolism
PB - American Pediatric Surgical Association
DB - APSA Webapp
DP - Unbound Medicine