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First described in 1864 by the German physician Rudolf Virchow and later named in 1910 by James Homer Wright, neuroblastoma (NB) remains an enigma despite decades of research and clinical experience. NB is an incredibly heterogeneous tumor with a natural history that ranges from regression and complete resolution to progression with metastasis and eventual death. The outcomes for patients with low and intermediate risk neuroblastoma has improved, largely through the recognition of the significant therapy related complications and a subsequent reduction in therapy intensity, although the survival for high risk disease remains poor.
Content in this topic is referenced in SCORE Neuroblastoma overview
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Last updated: October 24, 2018
Stafman, Laura, and Ihab Halaweish. "Neuroblastoma." Pediatric Surgery NaT, American Pediatric Surgical Association, 2018. APSA Webapp, www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829120/all/Neuroblastoma.
Stafman L, Halaweish I. Neuroblastoma. In: Waldhausen J, Powell D, Hirschl R, eds. Pediatric Surgery NaT. American Pediatric Surgical Association; 2018. https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829120/all/Neuroblastoma. Accessed April 18, 2019.
Stafman, L., & Halaweish, I. (2018). Neuroblastoma. In Waldhausen, J., Powell, D., & Hirschl, R. (Eds.), Pediatric Surgery NaT. Available from https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829120/all/Neuroblastoma
Stafman L, Halaweish I. Neuroblastoma [Internet]. In: Waldhausen J, Powell D, Hirschl R, editors. Pediatric Surgery NaT. American Pediatric Surgical Association; 2018. [cited 2019 April 18]. Available from: https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829120/all/Neuroblastoma.
TY - ELEC
T1 - Neuroblastoma
ID - 829120
A1 - Stafman,Laura,MD
AU - Halaweish,Ihab ,MD
ED - Waldhausen,John,
ED - Powell,David,
ED - Hirschl,Ron,
Y1 - 2018/10/24/
BT - Pediatric Surgery NaT
UR - https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829120/all/Neuroblastoma
PB - American Pediatric Surgical Association
DB - APSA Webapp
DP - Unbound Medicine