Immune Thrombocytopenia

Erik D Skarsgard, MD, MSc, Mary L. Brandt, MD

Introduction

Immune thrombocytopenia (ITP), previously called idiopathic thrombocytopenia, is a relatively rare autoimmune disorder that is characterized by isolated thrombocytopenia. As a result of the humoral antibody response against platelets, platelets are destroyed in a matter of hours instead of eight to ten days [1]. In some patients there may also be suppression of the megakaryocytes resulting in decreased production of platelets as well [1].

see alsoSplenic Disorders

Content in this topic is referenced in SCORE Splenic Diseases overviewHematologic Diseases: Spherocytosis, Sickle Cell, ITP, HSP overview

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Last updated: November 2, 2020