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Immune thrombocytopenia (ITP), previously called idiopathic thrombocytopenia, is a relatively rare autoimmune disorder that is characterized by isolated thrombocytopenia. As a result of the humoral antibody response against platelets, platelets are destroyed in a matter of hours instead of eight to ten days . In some patients there may also be suppression of the megakaryocytes resulting in decreased production of platelets as well .
see alsoSplenic Disorders
Content in this topic is referenced in SCORE Splenic Diseases overviewHematologic Diseases: Spherocytosis, Sickle Cell, ITP, HSP overview
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Last updated: August 3, 2018
Skarsgard, Erik D, and Mary L Brandt. "Immune Thrombocytopenia." Pediatric Surgery NaT, American Pediatric Surgical Association, 2018. APSA Webapp, www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829056/all/Immune_Thrombocytopenia.
Skarsgard ED, Brandt ML. Immune Thrombocytopenia. In: Waldhausen J, Powell D, Hirschl R, eds. Pediatric Surgery NaT. American Pediatric Surgical Association; 2018. https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829056/all/Immune_Thrombocytopenia. Accessed May 26, 2019.
Skarsgard, E. D., & Brandt, M. L. (2018). Immune Thrombocytopenia. In Waldhausen, J., Powell, D., & Hirschl, R. (Eds.), Pediatric Surgery NaT. Available from https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829056/all/Immune_Thrombocytopenia
Skarsgard ED, Brandt ML. Immune Thrombocytopenia [Internet]. In: Waldhausen J, Powell D, Hirschl R, editors. Pediatric Surgery NaT. American Pediatric Surgical Association; 2018. [cited 2019 May 26]. Available from: https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829056/all/Immune_Thrombocytopenia.
TY - ELEC
T1 - Immune Thrombocytopenia
ID - 829056
A1 - Skarsgard,Erik,MD, MSc
AU - Brandt,Mary,MD
ED - Waldhausen,John,
ED - Powell,David,
ED - Hirschl,Ron,
Y1 - 2018/08/03/
BT - Pediatric Surgery NaT
UR - https://www.pedsurglibrary.com/apsa/view/Pediatric-Surgery-NaT/829056/all/Immune_Thrombocytopenia
PB - American Pediatric Surgical Association
DB - APSA Webapp
DP - Unbound Medicine