The spleen is an important structure that has an evolutionary role as an organ of hematopoiesis in the fetus and essential roles in the acquisition of protective humoral immunity and red blood cell maintenance. A working knowledge of splenic anatomy and pathophysiology is necessary for the pediatric surgeon who will be called upon to treat splenic disorders arising from anatomic and immunologic disorders as well as red cell membrane abnormalities and hemoglobinopathies. The importance of multidisciplinary collaboration in the care of children with hematologic disorders requiring splenectomy is critical to mitigating the risk of perioperative complication and in optimizing the care of the asplenic patient.
Content in these topics is referenced in SCORE Splenic Diseases overviewHematologic Diseases: Spherocytosis, Sickle Cell, ITP, HSP overview
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