Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma, accounting for 4.5% of all childhood cancers. It is the third most common extracranial solid tumor of childhood, following Wilms tumor and neuroblastoma. RMS is a malignant neoplasm of mesenchymal origin, and is one of the small round blue cell tumors of childhood, along with neuroblastoma, lymphoma, and primitive neuroectodermal tumors (PNET). RMS can be located throughout the whole body with favorable locations like orbit, head and neck (nonparameningeal), and genitourinary (other than bladder, prostate, or kidney).
Content in this topic is referenced in SCORE Rhabdomyosarcoma overview
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